Technical Project Manager

Twist Bioscience is seeking a highly motivated and detail-oriented individual to support customer-driven Next Generation Sequencing (NGS) projects within a fast-paced, service laboratory. This role will work cross-functionally with Sales, R&D, Field Applications, and Customer Support teams to deliver high-quality sequencing data and solutions. The ideal candidate thrives in a dynamic environment, is highly organized, and is committed to maintaining production timelines while ensuring scientific excellence.
What You’ll Be Doing
Execute NGS library preparation, target enrichment, and sequencing workflows according to established protocols
Process samples for NGS analysis while meeting production schedules and customer timelines
Perform routine molecular biology techniques including PCR/qPCR, DNA quantification, purification (e.g., SPRI), and electrophoresis
Operate and maintain laboratory equipment, including liquid handling robots and sequencing platforms
Troubleshoot experimental and equipment-related issues to ensure continuity of workflows
Track multiple projects and samples simultaneously, ensuring accurate and detailed documentation (including batch records and deviations)
Analyze experimental data and contribute to interpretation of results
Support development, optimization, and execution of NGS-related protocols and workflows
Maintain digital files and records associated with sequencing runs
Ensure compliance with regulatory standards (e.g., ISO 13485) and internal quality requirements
Support general lab operations including cleaning, restocking, and maintaining a well-organized workspace
Collaborate effectively with cross-functional teams under aggressive timelines
What You’ll Bring to the Team
B.S. or M.S. in Molecular Biology, Biochemistry, Chemistry, or a related field (Associates degree with relevant experience may be considered)
Hands-on experience in molecular biology techniques such as PCR, DNA purification, quantification, and library preparation
Experience working in a laboratory environment with strong attention to detail and documentation practices
Ability to manage multiple tasks and prioritize effectively in a fast-paced environment
Strong organizational, planning, and problem-solving skills
Excellent interpersonal and communication skills with a collaborative mindset
Self-motivated with a commitment to delivering high-quality results
Preferred Qualifications
3–5 years of experience in molecular biology, NGS workflows, or a related field
Direct experience with NGS platforms (e.g., Illumina, PacBio, Element, ONT) and associated sample preparation workflows
Experience with NGS library preparation and target enrichment workflows
Experience with a range of NGS applications DNA, RNA, and Methylation assays
Strong familiarity with analytical tools such as BioAnalyzer or TapeStation, Qubit fluorometry and Nanodrop spectrophotometry
The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
San Francisco Bay Area Pay Range
$164,000—$203,000 USD