Chief of Staff / Business Strategy & Operations (BS&O) Manager (BioPharma) - REMOTE

REMOTE
We’re seeking to recruit highly motivated talent to join our exciting mission, in the development of innovative cell therapies and their application to the treatment of patients with cancer.
We are seeking a senior, versatile Chief of Staff / Business Strategy & Operations (BS&O) Manager to act as a strategic right hand and operational liaison to our commercial leadership team.
This is not a traditional technical or IT Project Manager role. It is a cross-functional hybrid position requiring a blend of business analysis, portfolio management, strategic consulting, and operational governance. The organization operates in a dynamic, fast-paced environment supporting a leadership team of 6 and a broader organization of ~20 members, managing over 100 simultaneous workstreams alongside internal and external stakeholders.
The ideal candidate functions as a force multiplier: structuring ambiguity, building governance from the ground up, keeping leadership accountable to core deliverables, and driving day-to-day strategic operations.
Key Responsibilities:
Strategic Operations & Executive Support (Chief of Staff Focus)
Partner directly with senior commercial leaders to align high-level strategic priorities with operational execution.
Facilitate executive cadence: prepare agendas, structure discussions, drive action tracking, and lead follow-through across cross-functional commercial teams.
Manage organizational budgets, operational spend, and financial planning in alignment with strategic business goals.
Bridge communication gaps across diverse functional teams (Sales, Marketing, Market Access, Analytics, and external vendor partners).
Portfolio Management & Program Governance
Maintain and optimize a portfolio of 100+ active workstreams using tools such as Smartsheet, SharePoint, and advanced Excel.
Establish frameworks, tracking cadences, and reporting dashboards where formalized processes do not yet exist.
Synthesize raw operational updates into clean, executive-ready presentations and dashboards for leadership review.
Monitor risks, dependencies, and delivery bottlenecks across competing workstreams.
Process Development & Change Enablement
Challenge existing operational workflows and build scalable operating rhythms from scratch.
Lead business change management initiatives to ensure sustainable adoption of newly introduced frameworks and processes.
Liaise with enterprise and IT digital transformation teams; act as a business-side translator without needing to execute technical implementation.
The Team
This is a key role in Client’s Global Digital, Data & Innovation team (GDDI) and reports to the Executive Director, Commercial.
The GDDI team are accountable for developing the vision, strategy, and roadmap for all digital technologies, data & analytics solutions used by Client’s Commercial function, and the customers it serves. GDDI collaborate with teams across the enterprise (Commercial, TechOps, Clinical, IT, Legal / Compliance etc.) to deliver on these capability roadmaps, with initiatives ranging in scale from multi-year digital transformation to ongoing enhancement of Commercial technologies delivered via agile release.
Your Responsibilities:
This role blends strategy, operations, governance, and execution leadership.
Core responsibilities include:
Strategy & Planning
Support development and execution of GDDI strategic priorities, annual objectives, and multi-year transformation roadmaps.
Translate executive strategy into clear operating plans, milestones, and outcomes.
Drive structured problem-solving and decision frameworks to inform leadership choices.
Portfolio & Investment Governance
Operate and evolve portfolio management and prioritization across GDDI initiatives
Support business case development, ROI tracking, and capacity / funding trade-off decisions
Enable transparent governance forums and executive readiness materials
Operating Model & Execution Excellence
Establish and run GDDI operating cadence (e.g. portfolio reviews, roadmap updates)
Partner with Commercial, IT, and Vendor leads to track execution against commitments
Identify risks, dependencies, and bottlenecks - driving mitigation plans early.
Transformation Enablement
Support large-scale programs including:
Digital and data platform modernization
AI strategy, implementation and scale-out
Global operating model evolution
Launch and scale-up readiness for new therapies and geographies
Enable cross-functional alignment across Commercial, Medica Affairs, TechOps, and IT
Change, Communications & Commercial Enablement
Drive change management and adoption strategies in partnership with program leads
Develop clear executive communications, narratives, and performance readouts
Strengthen documentation, knowledge management, and continuity practices
Performance Measurement & Value Realization
Define and track KPIs tied to business outcomes, adoption, and value delivery
Elevate insights on portfolio health, performance trends, and realized benefits
Required Knowledge, Experience & Skills
Strategic & Operational Experience
5+ years of experience in strategy, operations, transformation, or consulting roles
Demonstrated success operating in complex, matrixed, global environments
Experience supporting senior leadership and executive governance forums
Industry & Domain Knowledge
Experience in life sciences, healthcare, or regulated industries strongly preferred
Exposure to digital transformation, data & analytics, or enterprise platforms
Understanding of compliance, risk management, and enterprise delivery models
Analytical & Problem-Solving
Strong analytical mindset with ability to structure ambiguity and synthesize insights
Expertise building operating models, prioritization frameworks, and performance metrics
Communication & Influence
Exceptional written and verbal communication skills
Proven ability to influence without authority and align diverse stakeholders
Experience creating executive-ready materials and narratives
Ways of Working
Strong organizational discipline and attention to detail
Ability to manage multiple priorities while maintaining strategic perspective
Comfortable working in agile and hybrid delivery environments
Education & Certifications
Bachelor’s degree required; MBA or advanced degree preferred
Certifications in strategy, program management, agile, or change management all a plus
Our Core Values
Integrity: Doing what’s right.
Inclusion: Encouraging diversity.
Teamwork: Working together.
Excellence: Being your best.
Accountability: Taking personal responsibility.

Work arrangement
Yes