Principal Clinical Scientist

Principal Clinical Scientist (AI Training)
About The Role
What if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to frontier AI research — ensuring the clinical data and analyses powering next-generation AI systems meet the same exacting standards expected in real-world regulatory submissions.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to contribute to something genuinely new. No AI background required — just deep command of clinical research and a sharp eye for scientific quality.
Organization: Alignerr
Type: Hourly Contract
Location: Remote
Commitment: 10–40 hours/week
What You'll Do
Design and critically review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training
Interpret and audit clinical trial results for accuracy, consistency, and alignment with regulatory expectations
Evaluate AI-generated clinical analyses for scientific soundness and methodological integrity
Provide structured expert feedback that directly improves how AI models reason about clinical evidence, outcomes, and trial data
Work independently and asynchronously — fully on your own schedule
Who You Are
Senior-level experience designing clinical trial protocols intended for regulatory submission
Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent global bodies
Strong grounding in clinical research methodology, biostatistics, or translational science
Naturally detail-oriented with a rigorous, systematic approach to evaluating scientific quality
Clear and precise written communicator — able to document findings and feedback with authority
No prior AI or tech experience required
Nice to Have
Prior involvement in data annotation, data quality assurance, or evaluation systems
Experience reviewing or contributing to clinical evidence packages for drug, device, or diagnostic submissions
Background spanning multiple therapeutic areas or trial phases
Familiarity with AI-generated content or model evaluation workflows
Why Join Us
Work directly on frontier AI systems with real impact on clinical and biomedical research
Fully remote and flexible — work when and where it suits you
Freelance autonomy with the structure of meaningful, expert-level work
Influence how AI understands, evaluates, and communicates real-world clinical evidence
Potential for ongoing work and contract extension as new projects launch

Work arrangement
Yes