Principal Clinical Scientist

Principal Clinical Scientist (AI Training)
About The Role
What if your decades of clinical trial expertise could directly shape how AI understands and evaluates biomedical evidence for millions of researchers, clinicians, and patients worldwide?
We're looking for a Principal Clinical Scientist to bring senior-level authority in clinical trial design and regulatory-grade data interpretation into cutting-edge AI research workflows. Your expertise will help ensure that the AI systems influencing the future of clinical and biomedical science are built on rigorous, accurate, and regulation-ready foundations.
This is a fully remote, flexible contract role. No prior AI experience needed — just deep command of clinical trial methodology and regulatory science.
Organization: Alignerr
Type: Hourly Contract
Location: Remote
Commitment: 10–40 hours/week
What You'll Do
Design and critically review clinical trial protocols that generate high-quality, regulator-ready datasets for AI training and evaluation
Interpret and audit clinical trial results to verify accuracy, consistency, and alignment with regulatory standards
Evaluate AI-generated clinical analyses for scientific soundness and regulatory appropriateness
Provide expert, structured feedback to improve how AI models reason about clinical trial data, endpoints, and outcomes
Work independently and asynchronously — fully on your own schedule
Who You Are
Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
Strong grounding in clinical research methodology, biostatistics, or translational science
Naturally rigorous and detail-oriented — you hold clinical data to the highest standards
Clear and precise written communicator who can document scientific reasoning effectively
Comfortable working independently across varied clinical topics and therapeutic areas
Nice to Have
Prior experience with data annotation, data quality assurance, or evaluation frameworks
Familiarity with AI tools or model evaluation workflows as an end user
Background spanning multiple therapeutic areas or regulatory jurisdictions
Experience in medical writing, evidence synthesis, or systematic review
Why Join Us
Work directly on frontier AI systems shaping the future of clinical and biomedical research
Fully remote and flexible — work when and where it suits you
Freelance autonomy with the structure of meaningful, high-impact scientific work
Influence how AI understands, evaluates, and reasons about real-world clinical evidence at scale
Collaborate with leading AI research teams and labs on genuinely novel challenges
Potential for ongoing work and contract extension as new projects launch

Work arrangement
Yes