In Vivo Research Associate

In Vivo Research Associate
Do you want your in vivo work to help bring better treatments to people living with obesity and metabolic disease? As an In Vivo Research Associate in the Translational Pharmacology group at Zealand Pharma’s brand new research site in Cambridge, MA, you will run rodent studies and metabolic phenotyping that help decide which molecules move toward the clinic. If you want your experiments to matter to patients, we’d like to hear from you.
Your new position
As In Vivo Research Associate, you will be a hands-on contributor to preclinical studies that help advance Zealand Pharma’s drug candidates. The position covers the full study workflow, from preparing formulations and dosing animals to collecting and analyzing samples and documenting results. You will work closely with senior team members, gain broad exposure to in vivo pharmacology, and see your data feed into project team decisions. Flexibility to support dosing and sample collection on weekends and holidays, as studies require, is part of the role.
We offer exciting responsibilities:
Perform compound administration (SC, IP, IV, PO), body weight and food/water intake measurements, and clinical observations in mice and rats
Perform metabolic phenotyping, such as glucose and insulin tolerance tests, body composition analysis, and indirect calorimetry
Collect non-terminal blood samples and tissues on timed schedules for PK and PD studies, and conduct terminal procedures, including necropsy
Coordinate study logistics, including dosing schedules and sample collection plans
Support study setup, including animal randomization, baseline measurements, and blinding where applicable
Prepare compound formulations, dosing solutions, reagents, and buffers for in vivo studies
Process and analyze samples using standard laboratory techniques such as ELISA, plasma and tissue processing, and biochemical assays
Record data and maintain sample inventories accurately in the electronic lab notebook, and analyze and summarize study data in GraphPad Prism and Excel with guidance from senior team members
Present study results to the Translational Pharmacology group and project teams, and contribute to study reports
Monitor animal health, apply humane endpoints, and report concerns promptly, and conduct all work in compliance with IACUC, animal welfare, and biosafety requirements
Your profile
You are a careful, organized, and dependable team player who takes pride in accurate, well-documented work. You are comfortable handling multiple timelines and adapting when study needs change. You are curious, eager to learn from experienced colleagues, and committed to high standards of animal welfare.
BS/BA in biology, pharmacology, or a related field, and 1-2 years of hands-on in vivo experience in an academic or industry setting
Proficiency with core rodent techniques, including handling, dosing (SC, IP, IV, PO), and blood collection
Experience with standard laboratory techniques (e.g., ELISA, sample processing) and with preparing solutions or compound formulations
Working knowledge of IACUC requirements and good documentation practices
Proficiency with GraphPad Prism and Excel; experience with Benchling is a plus
Experience with metabolic phenotyping or stereotaxic surgery is a plus but not required
Your new team
You will join the Translational Pharmacology group within the Global Biology research organization, based at Zealand’s brand new research site in Cambridge, MA and focused on advancing new medicines for obesity and metabolic disease. The team collaborates closely with Chemistry, DMPK/Safety, Translational Medicine, and project teams across the US and Denmark, contributing to a portfolio of programs through robust in vivo data generation and interpretation.
Let’s bond and be bold
We have a unique culture, characterized by excellent teamwork and strong engagement across the organization. And we want you to help us strengthen this culture.
Making bonds is at the core of everything we do. From discovering and developing the best new peptide drugs for patients, to engaging with our partners or connecting with each other. We bond through curiosity and playfulness as a team, allowing ourselves to challenge common thinking and drive future innovation. Join us and let’s bond and be bold.
Interested in bonding with us? Please apply as soon as possible. The applications will be reviewed as they come in. While a cover letter is not required, please include a few sentences in your CV explaining your motivation for applying.
We are committed to an inclusive recruitment process and welcome applications from all job applicants.
About Zealand Pharma A/S
Zealand Pharma A/S (Nasdaq: ZEAL) is a biotechnology company focused on advancing medicines for obesity and metabolic health. Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health. To date, more than ten Zealand Pharma-invented drug candidates have entered clinical development, of which two products have reached the market and three candidates are in late-stage development. The Company has collaborations with global pharmaceutical and biotechnology partners for research, development, and commercialization. Founded in 1998, Zealand Pharma is headquartered in Copenhagen, Denmark, with a U.S. presence in Cambridge, Massachusetts. Learn more at www.zealandpharma.com.