Sr. Director, New Product Planning, Oncology

The Role
Building on the success of our platform in infectious diseases and positive INT data, Moderna is expanding its footprint in oncology. We are seeking a Senior Director of New Product Planning for our early oncology programs, from discovery through clinical proof of concept.
The Senior Director will shape product and development strategy across the early oncology portfolio. They will connect each program’s mechanism of action with disease biology to identify where it could deliver meaningful clinical benefit and change treatment decisions. Working with program leaders and colleagues across Research, Development, Commercial, and Manufacturing, they will translate that opportunity into target product profiles, indication and development choices, and recommendations on how programs and opportunities should be prioritized across the portfolio.
The successful candidate will bring demonstrated ability to lead program and portfolio strategy and a systems-thinking approach to integrating scientific, clinical, and market evidence. They will frame choices, lead cross-functional debate, and present recommendations to senior leaders on which opportunities to advance and where to focus investment and resources before development paths are fully defined.
Here’s What You’ll Do
Scientific and disease understanding
Develop a deep understanding of Moderna’s platform and its application to oncology.
Work with scientific and clinical colleagues to assess how each program’s mechanism of action could affect disease, including the implications of tumor biology, patient heterogeneity, and biomarkers.
Independently evaluate mechanistic, translational, and clinical evidence and its implications for program strategy, including disease progression and clinical endpoints.
Engage directly with scientific evidence and external experts to evaluate competing hypotheses and identify unresolved biological questions that affect development choices.
Market and competitive understanding
Understand how patients move through diagnosis, staging, biomarker testing, treatment selection, assessment, and subsequent treatment. Identify who makes each decision and how clinical evidence, physician judgment, patient preferences, and access shape those choices, including unmet needs within current standards of care.
Integrate market and competitive expertise into early program decisions.
Evaluate approved therapies, emerging mechanisms, and competitor programs, including their clinical evidence, development timelines, and potential strengths and limitations.
Develop scenarios for how standards of care and treatment pathways may evolve, including changes in treatment sequencing and the requirements for future differentiation.
Use direct conversations with KOLs, treating physicians, and other internal and external experts, together with scientific and market evidence, to test program assumptions and resolve questions that affect development choices.
Product and development strategy
Lead a disciplined strategy process with program teams: frame the choices, identify the information needed, structure debate around alternatives and tradeoffs, and make the logic for program decisions explicit.
Apply a biotech investment mindset to program development, identifying the most efficient path to reduce key risks and reach proof of concept. Define the evidence needed to justify further investment and adapt recommendations as data emerge.
Shape strategy and prioritization across the early oncology portfolio. Develop and present recommendations to senior leaders on which opportunities to advance and where to focus investment and resources, with clear alternatives, tradeoffs, and evidence gaps.
Integrate scientific, disease, market, and competitive insights to define where each oncology program can succeed and prioritize indications, patient populations, treatment settings, and lines of therapy.
Develop and refine target product profiles with program teams that connect the program’s mechanism of action and disease biology to a defined patient population, treatment setting, and clinical benefit. Define the efficacy, safety, durability, and dosing and administration requirements, together with the supporting evidence, needed for differentiation and to change treatment choices as standards of care evolve.
Shape clinical and evidence-generation plans, including patient selection, biomarkers, endpoints, and the evidence required for regulatory approval, physician adoption, reimbursement, and access.
Here’s What You’ll Bring to the Table (Basic Qualifications)
Bachelor’s degree or higher in a scientific, medical, business, or related field.
At least 10 years of experience in the pharmaceutical or biotechnology industry, including significant experience in new product planning, research strategy, program leadership, global marketing, portfolio strategy, or a related function.
Demonstrated experience leading product and portfolio strategy across multiple programs in discovery and early clinical development, including influencing senior decisions on program advancement, investment, and resource allocation.
Strong understanding of oncology biology and clinical development, with the ability to independently evaluate mechanistic, translational, and clinical evidence and connect it to treatment decisions.
Here’s What You’ll Bring to the Table (Preferred Qualifications)
Experience in oncology, including familiarity with treatment pathways, clinical endpoints, patient segmentation, and the evolving competitive landscape.
Strong analytical skills and the ability to build, challenge, and communicate assumptions.
Demonstrated ability to use AI-supported evidence workflows to investigate program questions, test competing explanations, evaluate underlying sources, and identify when expert input or additional data is needed.
Strong written and verbal communication skills, including the ability to present a concise recommendation to senior leaders and defend it objectively.
The ability to influence across functions without direct authority, lead teams through competing views, and establish productive working relationships with scientific, clinical, and commercial colleagues.
Our Working Model
As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.
Moderna is a smoke-free, alcohol-free, and drug-free work environment.
Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.
Competitive healthcare, plus voluntary benefit programs to support your unique needs
A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
Family planning benefits, including fertility, adoption, and surrogacy support
Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
Savings and investments to help you plan for the future
Location-specific perks and extras
The salary range for this role is $196,700.00 - $353,400.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.

The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Equal Opportunities