Principal Scientist / Senior Principal Scientist - Peptide Synthesis

Let’s build the future of medicine—together.
Genome Valley, Hyderabad, India | Full-Time
YOUR ROLE
As Senior Principal Scientist / Principal Scientist, Peptide Synthesis at Enveda, you will build and lead our peptide synthesis group from the ground up. You will set up the lab, define synthesis, purification and QC standards, and grow a team of 3-4 chemists who turn sequences designed by our project teams into high-purity, well-characterised peptides for therapeutic programmes. The role starts hands-on at the bench and moves toward leadership as the team matures.
WHAT YOU'LL DO
Synthesise linear, cyclic, lipidated and modified peptides by Fmoc SPPS (manual, microwave and automated), including orthogonal on-resin chemistry for branching and cyclisation
Troubleshoot difficult sequences (aggregation, racemisation, aspartimide formation) and give the design team early feedback on synthetic feasibility
Guide preparative RP-HPLC purification, interpret HPLC and LC-MS data, and decide between re-purification, re-synthesis and release
Set up the lab: specify and qualify synthesisers and lyophilisers, write SOPs, and partner with CROs/CDMOs for scale-up
Hire, train and mentor 3-4 chemists; plan workloads, run technical reviews and build a strong safety culture

Experience
8+ yrs

Employment type
Full-time

Work arrangement
No