Senior Software Engineers

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Position: Senior Software Engineers
Employer: Sigma-Aldrich Corporation
400 Summit Drive
Burlington, Massachusetts 01803
Job Site: 3050 Spruce Street
St. Louis, MO 63103
Telecommuting: Telecommuting is available up to three (3) days per week.
Responsibilities:
Design, develop, and test scalable web applications using Java and JavaScript/TypeScript (React) in a regulated life sciences environment;
Architect and model relational and non-relational database schemas for scientific and laboratory data;
Lead high-level system design of microservices and component-based software architectures;
Configure, deploy, and manage secure AWS cloud infrastructure and web services using infrastructure-as-code;
Build software that integrates with laboratory instruments/devices, including instrument calibration workflows and acquisition of scientific measurement data;
Develop data-visualization interfaces that present chemistry and laboratory data to scientists for analysis and decision-making;
Ensure applications meet GxP and ISO quality, validation, and data-integrity standards for regulated certified products;
Collaborate directly with scientists and chemists to translate laboratory, chemistry, and analytical requirements into maintainable software designs;
Apply AI-assisted / agentic developer tooling (e.g., MCP-based workflows, design-to-code automation) to accelerate delivery; and
Conduct code reviews, resolve production issues, prepare technical documentation and architecture diagrams, and mentor peers.
Requirements & Qualifications:
Employer requires candidate to have at least a Master’s degree in Computer Science, Information Science & Technology, or a closely related technical field. Candidate must also have at least three (3) years of work experience as a software engineer or a closely related occupation.
Candidate must also have the following:
Demonstrated professional proficiency in full-stack application development, encompassing server-side systems engineering utilizing Java and user-interface development using the React framework gained through at least two (2) years of work experience.
Demonstrated ability developing software in a regulated life sciences environment under GxP and ISO quality/compliance standards (data integrity, validation, documentation) gained through at least one (1) year of work experience.
Demonstrated ability building software that integrates with laboratory instruments/devices, including instrument calibration workflows and data visualization of scientific/chemistry data, in collaboration with s