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Date: 1 Sept 2026
Location:
Bangalore, KA, IN, 560099
Division: Discovery Services
Job Description
Job Title: Principal Scientist – Assay Biology
Job Location: Bangalore
About Syngene: Syngene (www.syngeneintl.com) is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit
Mandatory expectation for all roles as per Syngene safety guidelines
Overall adherence to safe practices and procedures of oneself and the teams aligned
Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
Compliance to Syngene’ s quality standards at all times
Hold self and their teams accountable for the achievement of safety goals
Core Purpose Of The Role
Senior Scientist to support in vitro research activities that are critical to Bicara project.
Key Roles And Responsibilities
Cell based Assays & Functional Studies
Conduct studies to assess anti-tumor activity across various tumor cell lines and indications.
Execute and optimize 2D and 3D co culture experiments incorporating PBMCs, stromal cells, and other relevant cell types.
Independently plan and perform a diverse portfolio of assays including:
Flow cytometry
Cell proliferation and inhibition assays
Cytokine & Biomarker Profiling
Luminex
ELISA
Cytometric Bead Array (CBA)
Imaging & Kinetic Assays: Utilize and optimize Incucyte based real time imaging to monitor cell proliferation, apoptosis, cytotoxicity, and cell cell interactions.
Data Analysis and Documentation
Analyze large experimental datasets using standard software tools and prepare study summaries for internal reviews and cross-functional meetings.
Maintain rigorous, timely, and compliant documentation in Electronic Lab Notebooks (ELNs).
Compliance & Data Integrity
Ensure adherence to organizational safety, quality, and EHSS standards.
Follow ALCOA+ principles and maintain accurate electronic lab notebook (ELN) records.
Laboratory Operations
Support routine lab activities including mammalian cell culture.
Reagent preparation and aliquoting
Logging and tracking of appropriate storage and inventory of critical reagents
Specific Requirements For This Role
Education
Master’s degree (M.Sc.) or PhD in:
Biology / Biotechnology
Immunology / Cell Biology
Cancer Biology or related life sciences field
Experience
Scientist: 7-8 years of relevant industry experience post MSc. or 2years post PhD.
Hands-on experience (preferred) in:
Cell-based assays (proliferation, cytotoxicity)
Mammalian cell culture
Immunoassays (ELISA, Luminex, CBA)
Flow cytometry
Experience with data analysis tools (e.g., PLA, SoftMax Pro, GraphPad Prism, Excel)
Core Competencies
Strong interpersonal, analytical, presentation, and communication skills.
Ability to work effectively under tight timelines in a collaborative environment.
Syngene Values
All employees will consistently demonstrate alignment with our core values
Excellence
Integrity
Professionalism
Equal Opportunity Employer
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodation for qualified individuals with disabilities.
Work arrangement
No
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