Principal Clinical Scientist

Principal Clinical Scientist (AI Training)
About The Role
What if your years of clinical trial expertise could directly shape how AI reasons about biomedical evidence — influencing systems that will impact research and patient outcomes for years to come?
We're looking for a Principal Clinical Scientist to bring senior-level rigor into cutting-edge AI development. You'll work alongside world-leading AI research teams, ensuring that the clinical data and reasoning embedded in frontier AI models meets the standards you'd expect in a real-world regulatory submission.
This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work on their own terms.
Organization: Alignerr
Type: Hourly Contract
Location: Remote
Commitment: 10–40 hours/week
What You'll Do
Design and review clinical trial protocols used to generate high-quality, regulator-ready training datasets
Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations (FDA, EMA, or equivalent)
Provide expert, structured feedback that directly improves how AI models reason about clinical trial data and outcomes
Work independently and asynchronously — fully on your own schedule
Who You Are
Senior-level experience designing clinical trial protocols intended for regulatory submission
Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies
Strong command of clinical research methodology, biostatistics, or translational science
Naturally rigorous and detail-oriented — you hold your work to the same standards regulators do
Clear, structured communicator who can articulate complex scientific reasoning in writing
Nice to Have
Prior experience with data annotation, data quality review, or evaluation systems
Background in AI-adjacent roles such as digital health, clinical decision support, or health informatics
Familiarity with how AI systems are trained and evaluated
Why Join Us
Work directly on frontier AI systems shaping the future of clinical and biomedical research
Influence how AI understands, evaluates, and reasons about real-world clinical evidence
Fully remote and flexible — work when and where it suits you
Freelance autonomy with the structure of meaningful, high-impact work
Collaborate with leading AI research teams and labs globally
Potential for ongoing work and contract extension as new projects launch

Work arrangement
No