Principal Clinical Scientist

Principal Clinical Scientist (AI Training)
About The Role
What if your expertise in clinical trial design and regulatory science could directly shape how AI understands and interprets biomedical evidence? We're looking for a Principal Clinical Scientist to bring senior-level clinical rigor to cutting-edge AI research — helping ensure that the AI systems influencing the future of medicine are built on scientifically sound, regulatory-grade foundations.
This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful work at the intersection of clinical research and frontier AI.
Organization: Alignerr
Type: Hourly Contract
Location: Remote
Commitment: 10–40 hours/week
What You'll Do
Design and review clinical trial protocols used to generate high-quality, regulatory-ready datasets for AI training and evaluation
Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
Evaluate AI-generated clinical analyses for scientific soundness and compliance with the expectations of agencies such as the FDA, EMA, or equivalent bodies
Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
Apply your knowledge of clinical research methodology to identify gaps, errors, and areas for improvement in AI-generated outputs
Who You Are
Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
Deep expertise interpreting clinical data in the context of FDA, EMA, or equivalent regulatory frameworks
Strong grounding in clinical research methodology, biostatistics, translational science, or a closely related discipline
Sharp eye for scientific accuracy and regulatory relevance — you know when something doesn't meet the bar
Self-motivated, reliable, and comfortable working independently in an asynchronous environment
Nice to Have
Prior experience with data annotation, data quality workflows, or AI evaluation systems
Background in pharmacovigilance, medical writing, or health technology assessment
Familiarity with AI tools or scientific content evaluation platforms
Experience working across therapeutic areas or with cross-functional regulatory teams
Why Join Us
Work directly on frontier AI systems that are shaping the future of clinical and biomedical research
Influence how AI understands, evaluates, and reasons about real-world clinical evidence
Fully remote and flexible — work when and where it suits you
Freelance autonomy with the structure of meaningful, expert-level work
Collaborate with world-leading AI research teams and labs
Potential for ongoing work and contract extension as new projects launch

Work arrangement
No