Principal Software Engineer

About Us
Endpoint is an interactive response technology (IRT®) systems and solutions provider that supports the life sciences industry. Since 2009, we have been working with a single vision in mind, to help sponsors and pharmaceutical companies achieve clinical trial success. Our solutions, realized through the proprietary PULSE® platform, have proven to maximize the supply chain, minimize operational costs, and ensure timely and accurate patient dosing. Endpoint is headquartered in Raleigh-Durham, North Carolina with offices across the United States, Europe, and Asia.
We ʼ re seeking a principal software engineer who is passionate, experienced and skilled, versatile, and customer-and business- oriented. In this role, we will also need someone who is full-stack and polyglot (see specific technologies below). This is a critical technical leadership role. As a principal engineer you will define the technical direction of our forecasting product, allowing us to scale and mentoring other engineers. You will also operate as a primary technical authority across multidisciplinary teams, partnering tightly with customers, partners and especially internal stakeholders, translating fundamental needs into technological solutions that drive the business.
Responsibilities
Partner closely with product and executive leadership to inform and implement company strategy. Work with internal stakeholders such as Product and UX to rapidly distill initially ambiguous requirements into concrete and actionable plans
Be a strong, hands-on contributor delivering code and features day-to-day
Drive technical strategy and architecture for our product across all engineering domains
Champion operational excellence: reliability, quality, and continuous risk reduction across the product. Document and oversee implementation of the engineering standards that ensure it.
Own the security and compliance posture appropriate our product, e.g. SOC 2,data integrity, and potentially GxP/21 CFR Part 11 consideration
Accelerate application development and uplevel engineering staff via mentorship and selecting relevant trainings, conferences, and events for the team
Help grow the team: interviewing, hiring, and raising the technical bar as we scale
Represent engineering with customers and other internal and external stakeholders
Be AI-literate, leveraging the latest technologies to inform the technical and
Product roadmap. You will educate internal stakeholders on how the latest technologies work and contribute key ideas to conversations about how they can be leveraged in the product
Experience
12+ years of engineering excellence
A proven track record of architecting, scaling, and maintaining complex, scaled systems
Past responsibilities involve systems with large numbers of users in environments where quality, security, and reliability are critical
Polyglot mastery and a proven ability to learn new languages and architectures.
Ability to hit the ground running — someone who is already proficient in our current stack
Education
Bachelors degree or higher in Computer Science or other relevant field preferred
Skills Required
Should be expertise in front end technologies: TypeScript, React
Should have good experience in NodeJS
Rust ideally (ideally), or Go/C++
Amazon Web Services and Azure (ideally), or equivalent
CI/CD: GitHub Actions, or equivallent
Infrastructure-as-code solutions like Terraform, Pulumi or equivalent
$160,000 - $170,000 a year
Endpoint Clinical does not accept unsolicited resumes from search firms or any other third parties. Any unsolicited resume sent to Endpoint Clinical will be considered Endpoint Clinical property, and Endpoint Clinical will not pay a fee should it hire the subject of any unsolicited resume.
Endpoint Clinical is an equal opportunities employer AA/M/F/Veteran/Disability.
Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment, qualified applicants with arrest and conviction records.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Work arrangement
Yes