MES Engineer

Job Title: MES Engineer
Location : Hyderabad
Experience : 8 Years
Job Summary
We are seeking an experienced MES Engineer to support the design, configuration, implementation, and integration of Manufacturing Execution Systems (MES) in pharmaceutical or regulated manufacturing environments. The ideal candidate will have hands-on experience with PAS-X, Rockwell FactoryTalk Batch, FactoryTalk View SE, Rockwell PLCs, and SQL databases.
Key Responsibilities
Author, configure, and maintain Master Batch Records (MBRs) and Electronic Batch Records (EBRs) to digitize paper-based manufacturing processes.
Configure and implement MES workflows to support pharmaceutical manufacturing operations in compliance with GMP and data integrity requirements.
Integrate MES platforms with PLCs, SCADA, and other manufacturing systems using OPC UA/DA, MQTT, and related communication protocols.
Develop and configure operator prompts, electronic signatures, dynamic workflows, and formula-driven parameters.
Implement in-process checks, exception handling, and real-time alarm management to ensure safe and compliant manufacturing operations.
Configure backend logic to trigger automated system actions, operator notifications, and exception workflows.
Work with SQL databases to query, validate, troubleshoot, and manage manufacturing-related data.
Support the integration of MES with automation systems, equipment, and enterprise applications.
Troubleshoot MES configuration, communication, and system integration issues.
Participate in system testing, including FAT, SAT, IQ/OQ, and validation activities, as applicable.
Collaborate with Manufacturing, Quality Assurance, Engineering, Automation, and IT teams to resolve technical issues and improve manufacturing processes.
Maintain system documentation, configuration specifications, and change-control records in accordance with applicable procedures.
Required Technical Skills
MES Platforms: Siemens Opcenter Execution Pharma (formerly SIMATIC IT eBR/PAS-X, where applicable) or Werum PAS-X.
Rockwell Automation: FactoryTalk Batch, FactoryTalk View SE, and Rockwell PLCs.
Database: SQL and relational database management systems (RDBMS).
Communication Protocols: OPC UA, OPC DA, MQTT, and industrial communication interfaces.
Manufacturing Standards: ISA-88 batch control architecture and ISA-95 enterprise-to-control system integration.
Knowledge of electronic batch records, master batch records, electronic signatures, alarm management, and exception handling.
Understanding of pharmaceutical GMP, data integrity, and computerized system validation.
Education and Experience
Bachelor's degree in Chemical Engineering, Biomedical Engineering, Chemistry, Biology, Computer Science, or a related technical field; equivalent relevant education and experience may be considered.
Hands-on experience configuring or supporting MES platforms in pharmaceutical, biotechnology, life sciences, or other regulated manufacturing environments.
Practical experience with MES-to-PLC/SCADA integration and SQL-based data handling.
Strong troubleshooting, analytical, documentation, and communication skills.
Preferred Qualifications
Experience with pharmaceutical manufacturing processes and electronic batch record implementation.
Familiarity with GAMP 5, 21 CFR Part 11, and electronic record and signature compliance requirements.
Experience with system integration testing, commissioning, validation, and production support.
Ability to work collaboratively with cross-functional teams in a GMP-regulated environment.

Work arrangement
No