MES Engineer

Work Your Magic with us! Start your next chapter and join MilliporeSigma.
Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.
This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.
Your Role
The MES Engineer supports the effective use and continuous improvement of Siemens Opcenter MES at the Jaffrey site. This role provides day-to-day user and operational support, troubleshooting, business-facing configuration updates, and coordination with IT and cross-functional teams to help ensure MES supports site operations, quality, and compliance requirements. The role works closely with site SMEs, Operations, Quality, Validation, Automation, IT, and global digital teams, and may also support future MES expansion activities.
Key Responsibilities:
Perform MES modeling and configuration changes and enhancements to address operational needs, improve user experience, and align system use with site processes and user requirements.
Resolve workflow, reporting, integration, and usage issues in MES, in collaboration Opcenter SME and cross-functional teams.
Work with IT to support resolution to issues affecting Production uptime as needed.
Support equipment and enterprise system interfaces by monitoring data flow, troubleshooting issues, and coordinating enhancements with cross-functional teams.
Lead change management activities for all MES maintenance and improvement initiatives for existing deployments, with support from the cross-functional team.
Perform change assessments and support qualification and validation activities for system updates, fixes, and enhancements
Create and maintain technical documentation aligned with GAMP, SDLC, and site procedures
Ensure MES-related activities comply with GxP, data integrity, EHS, and quality requirements
Partner with Operations, Quality, Validation, Automation, IT, and other teams to support continuous improvement and effective site use of MES
Who You Are
Minimum Qualifications:
Bachelor’s degree in STEM, engineering, computer science, technical management, or a related field
5+ years of manufacturing experience
2+ years of experience supporting manufacturing, OT, MES, or related digital systems in a production environment
Basic knowledge of manufacturing process support and system troubleshooting
Knowledge of or willingness to learn Siemens Opcenter MES configuration, including modeling objects, business rules, expressions, user queries, and integrations
Preferred Qualifications:
Working Knowledge of ISO & FDA regulations (such as ISO 9001, ISO 13485 or 21 CFR 820, 210 & 211).
Knowledge of SQL queries, SAP Business Objects, or related reporting and data tools
Familiarity with equipment integration and interface support, including OPC UA or similar connectivity