Site Head, Mirus Bio

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Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.
This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.
Your Role:
The Site Head is accountable for the on-time manufacturing of high-quality products in a safe, cost-efficient, and environmentally responsible manner. This strategic leadership role defines and drives the site’s operational vision, fostering an autonomous culture that promotes team ownership, accountability, and innovation.
This role is responsible for establishing and executing the long-term operational roadmap for the site while ensuring organizational readiness for future growth, operational excellence, and enterprise alignment. The Site Head will oversee Manufacturing, Supply Chain, Quality, Facilities, EHS and related operational functions while driving integration initiatives across systems, processes, governance, and infrastructure with MilliporeSigma.
The ideal candidate combines strategic leadership with hands-on operational rigor and has a demonstrated ability to scale life science operations in a fast-paced environment supporting complex product portfolios across RUO and GMP environments.
Key Accountabilities:
Strategic Operations Leadership
Accountable for the on-time manufacturing of high-quality products in a safe, cost-efficient, and environmentally responsible manner
Develop and execute the multi-year strategic roadmap for site Operations aligned with growth objectives aligned and global/cluster objectives
Build scalable operational capabilities to support future commercial growth, product launches, and evolving customer requirements.
Drive operational excellence initiatives focused on throughput, reliability, cost optimization, and organizational scalability.
Establish KPI-driven management systems and governance processes to improve accountability, visibility, and execution discipline.
Accountable for the development and execution of the site strategic vision aligned with global/cluster objectives and overall manufacturing performance
Oversees budgeting, cost control, and resource allocation across site operations to ensure alignment with strategic and financial objectives.
Responsible for facility management including ownership of vendor contracts, lease management, and engineering/maintenance management (Mirus Bio site)
Quality & ISO9001 Leadership
Accountable for the strategic Quality roadmap for the organization, including development and execution of an enterprise-ready ISO9001 framework.
Lead efforts to strengthen Quality Systems, documentation practices, risk management, deviation management, and CAPA effectiveness.
Ensure timely and sustainable CAPA closure activities through strong cross-functional accountability and root-cause analysis methodologies.
Partner with Regulatory, R&D, Manufacturing, and Commercial teams to ensure quality standards support both innovation and operational scalability.
Build inspection and audit readiness capabilities consistent with enterprise expectations and customer requirements.
Supply Chain & External Network Optimization
Develop and implement a robust secondary supplier strategy to improve supply continuity, resiliency, and risk mitigation across critical materials and components.
Optimize the external CDMO and supplier network to support scalability, quality, service levels, and cost efficiency.
Establish supplier governance frameworks, performance metrics, and risk management processes across external partners.
Partner with sourcing and procurement teams within MilliporeSigma to leverage enterprise capabilities and strategic supplier relationships.